部分液体通气治疗重症COVID-19

Request professional help for tralation into English.大家好：我提供一点建议，目前呼吸机短缺的主要原因一方面是病人数量骤增，形成医疗资源挤兑，另一方面不得不说，现在的高流氧治疗方案抢救成功率低。因此我们提议以目前用于救治早产儿的液体介质呼吸用于治疗重型和危重型COVID-19。从文献了解，液体通气可以通過清除粘液阻塞來幫助增加氧氣的吸收，改善通气 / 血流比值,改善机体氧合状况。局部消炎作用，在体外抑制肺泡巨噬细胞对异物的反应性。重型和危重型COVID-19患者的肺部被病毒导致的果冻状的分泌物占据，换气功能完全丧失，高压力流氧方案不能去除黏液，很多时候还会导致病情加重。液体介质呼吸治疗方案以PFC为通气介质，通过雾化或汽化吸入通气干预呼吸衰竭的过程。具体方法是在常规机械通气基础上，经呼吸机吸气管路以湿化器加热 PFC 的方法给予汽化吸入 PFC 治疗 2 小时，然后继续常规机械通气 6 小时。为了提高治疗效果，综合采用包括肺保护性通气、肺复张、俯卧位通气等通气策略。如果临床治疗有效，将极大提高呼吸机的利用率，部分解决呼吸机短缺问题。With cases of the new coronavirus disease 2019 (COVID-19) climbing steeply everywhere from Madrid to Manhattan , overwhelming one hospital after another and pushing the global death toll past 23,000, the sprint to find treatments has dramatically accelerated. The World Health Organization (WHO) last week announced a major study to compare treatment strategies in a streamlined clinical trial design that docto around the world can join. Other trials are also underway; all told, at least 12 potential COVID-19 treatments are being tested, including drugs already in use for HIV and malaria, experimental compounds that work agait an array of viruses in animal experiments, and antibody-rich plasma from people who have recovered from COVID-19. More than one strategy may prove its worth, and effective treatments may work at different stages of infection, says Thomas Gallagher, a coronavirus researcher at Loyola Univeity Chicago's Health Sciences severe cases of COVID-19 a patient’s lungs become inflamed and filled with fluid which makes it difficult for them to breathe. in these cases hyperoxia therapy get low rescue success breathing is a form of respiration in which a normally air-breathing organism breathes an oxygen-rich liquid (such as a perfluorocarbon), rather than breathing air, include Total liquid ventilation and Partial liquid ventilation(PLV).Liquid breathing could assist in the treatment of patients with severe pulmonary or cardiac trauma, especially in pediatric cases. PFC emulsio could prove an effective new way to eliminate inflammation and mucus during the drug delivery process, decreasing the risk of chronic infection while increasing the patient’s ability to breathe deeply. Liquid ventilation, minus the drugs, is already seeing use in neonatal units on premature infants with underdeveloped lungs. The method has even been coidered as an alternative to intravenous (IV) drug delivery in some itances. Unlike IV delivery, drugs delivered through the lungs bypass the fit pass through the liver, which can often filter much of the medication from the blood before it has a chance to reach the rest of the body. live we need to breathe. Prior to being born we carry this activity out through the placenta and subsequently by mea of our lungs. ation of science fiction respiration respirator simulates placentary respiration by filling the lungs of the premature baby with liquid and then the respirator introduces and extracts the required quantity of liquid at a suitable respiratory rhythm.